Vancomycin AUC Calculator Renal driver → Initial dosing · Trough-only AUC · Peak & trough
Acid·Base Vancomycin
Patient & renal labs START HERE
years
yr
for Cockcroft-Gault
stature
body weight
0.6–1.2 mg/dL
0.5–1.0 mg/L
auto-selects by BMI
IDMS-traceable

▸ Special populations — amputation, SCI, paralysis
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Target & regimen AUC-GUIDED
Clearance source: none yet — run the Renal tab, or enter CL manually below
years
yr
actual body weight
kg
from renal driver · mL/min
mL/min
mg/kg
population clearance 0.75 × CrCl + 4 (ml/min)
volume of distribution 0.29×age + 0.33×wt + 11 (L)
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Current regimen & level SS TROUGH
per dose
dosing frequency
per dose
min
steady-state Css
mcg/mL
years
yr
actual body weight
kg
population volume 0.29×age + 0.33×wt + 11 (L)
Timing entry
before next dose
hr

Confirm steady state: 4–5 half-lives elapsed, stable renal function, dose before the trough given on time (±1 h).

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Regimen & two levels TWO LEVELS
per dose
dosing frequency
post-distribution
mcg/mL
end of interval
mcg/mL
Level timing
min
hr
after end of infusion
hr
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For use by licensed clinicians. First-order one-compartment estimates — verify against institutional protocol and clinical context. AUC24 400–600 for serious MRSA; sustained >650 raises nephrotoxicity risk. Population CLv models were derived from Cockcroft-Gault CrCl; eGFR drivers are de-indexed to BSA and run off-calibration.